Scaffolds for Bone Tissue Restoration from Biological Apatite

نویسندگان

  • R. Murugan
  • T. S. Sampath Kumar
  • S. Ramakrishna
چکیده

A great deal of effort has been exerted to design scaffolds for bone tissue restoration from naturally-derived biomaterials that mimic the composition and structure of natural bone. This article reports a simple method for processing biological apatite (BAp) from bovine bone. Chemical and low temperature heat treatments were employed for the processing of BAp scaffold. Phase composition, microstructure, and compressive strength were examined by various analytical methods. The results indicated that the phase composition and crystalline structure of BAp correspond to the hydroxyapatite (HAp) phase. The SEM observation showed that the BAp possesses porous morphology and the pores are in the range of micrometers to nanometers in diameter. Despite the porous structure, the scaffold possesses adequate mechanical strength required for low-weight bearing orthopedic applications. The overall experimental results therefore suggest that the BAp may be used as scaffolds for bone tissue restoration.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Hydroxyapatite-Hardystonite nanocomposite scaffolds prepared by the replacing the polyurethane polymeric sponge technique for tissue engineering applications

Objective (s): Silicate bioceramics containing Zn and Ca like hardystonite (Hr) with chemical formula Ca2ZnSi2O7 has attracted the attention of researchers in biomedical field due to its remarkable biological and mechanical properties. The new generation of bioceramics can applied in bone tissue engineering to substitute with infected bone. However, these zirconium-silicate bioceramics have pro...

متن کامل

Evaluation of mechanical properties and apatite formation of synthesized fluorapatite-hardystonite nanocomposite scaffolds

In this study, mechanical properties and apatite formation ability of synthesized fluorapatite-hardystonite (FA-HT) nanocomposite scaffolds were investigated. Hardystonite (HT; 5 and 10 wt.%) as a reinforcement phase was incorporated into the FA scaffold. FA was mixed with HT for 4 h under argon gas at 220 °C. A space holder method was used for fabricating porous FA-HT scaffolds. Sodium chlorid...

متن کامل

A novel three-dimensional printing of electroconductive scaffolds for bone cancer therapy application

Objective(s): Tissue engineering aims to achieve a tissue, which has highly interconnected porous microstructure concurrent with appropriate mechanical and biological properties. Materials and Methods: Therefore, the microstructure scaffolds are of great importance in this field. In the present study, an electroconductive poly-lactic acid (EC-PLA) filament used to fabricate a porous bone ...

متن کامل

A Review on Commonly Used Scaffolds in Tissue Engineering for Bone Tissue Regeneration

Introduction: Bone is one of the tissues that have a true potential for regeneration. However, sometimes the bone defects are so outsized that there is no chance of bone self-repair and restoration or the damage is such that it is not possible to repair with medical or surgical interventions. In these situations, bone grafts are the treatment of choice, but due to several obstacles, including l...

متن کامل

Improving the mechanical and bioactivity of hydroxyapatite porous scaffold ceramic with diopside/forstrite ceramic coating

Objective(s): Scaffolds are considered as biological substitutes in bone defects which improve and accelerate the healing process of surrounding tissue. In recent years a major challenge in biomaterials is to produce porous materials with properties similar to bone tissue. In this study, the natural bioactive hydroxyapatite scaffolds with nano Diopside /Forstrite coating was successfully synthe...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2006